"It's not about how to achieve your dreams. It's about how you lead your life. If you lead you life the RIGHT WAY, the karma (destiny, fortune, good luck) will take care of itself. The dreams will come to you." 
                                                  -Dr. Randy Pausch
This quote means that how you get towards your dreams doesn't matter what matters is the actions and steps you do to get to your dreams. Take positive actions. Choose the right. If you decide to take the wrong path and make negative actions karma will follow you. We all know that karma isn't a good thing at all. Take responsibility for your life. Live it the right way. An example of this quote would be someone lying to another person. Karma will follow you for doing bad and not good. So choose the right and your dreams will come true within time.